Chip comparison
AMD Instinct MI250X vs AMD Instinct MI350 series
Side-by-side specs
Straight from each vendor's datasheet. Winner in bold: higher throughput, memory, or transistor count; lower power draw or price. Sparse (2:4) throughput roughly doubles the FP8/INT8 numbers shown.
| Field | AMD Instinct MI250X | AMD Instinct MI350 series |
|---|---|---|
| Process node | TSMC N6 | TSMC N3 (chiplet) |
| TDP | 560 W | 1000 W |
| Memory | 128 GB HBM2e | 288 GB HBM3e |
| Memory bandwidth | 3,200 GB/s | 8,000 GB/s |
| FP16 (dense) | 383 TFLOPS | 2,300 TFLOPS |
| BF16 (dense) | 383 TFLOPS | 2,300 TFLOPS |
| FP8 (dense) | — | 4,600 TFLOPS |
| INT8 (dense) | 383 TOPS | 4,600 TOPS |
| Form factor | OAM | OAM |
| Announced | 2021-11-08 | 2025-06-12 |
| Released | 2022-06-01 | 2025-10-01 |
Robots running AMD Instinct MI250X
No robots publicly running it yet.
Robots running AMD Instinct MI350 series
No robots publicly running it yet.
Data centers with AMD Instinct MI250X
No data centers publicly running it yet.
Data centers with AMD Instinct MI350 series
Common questions
AMD Instinct MI250X vs AMD Instinct MI350 series: which is faster for training?
AMD Instinct MI350 series has 12.01x the dense FP16/BF16 throughput of the other (AMD Instinct MI250X: 383 TFLOPS; AMD Instinct MI350 series: 4,600 TFLOPS). Real-world training speed also depends on memory bandwidth, interconnect, and software stack: see the spec diff for those inputs.
AMD Instinct MI250X vs AMD Instinct MI350 series: which has more memory?
AMD Instinct MI350 series carries more HBM (AMD Instinct MI250X: 128 GB HBM2e; AMD Instinct MI350 series: 288 GB HBM3e). Memory capacity sets the largest model that fits on one chip without partitioning; memory bandwidth sets inference throughput.
AMD Instinct MI250X vs AMD Instinct MI350 series: which is more power-efficient?
Dense FP16/BF16 TFLOPS per watt: AMD Instinct MI250X 0.68 (383 ÷ 560 W); AMD Instinct MI350 series 4.60 (4,600 ÷ 1000 W). AMD Instinct MI350 series wins at the die level; system-level efficiency also depends on cooling and interconnect.
AMD Instinct MI250X vs AMD Instinct MI350 series: which is more widely used?
AMD Instinct MI250X: 0 robots and 0 data centers publicly running it. AMD Instinct MI350 series: 0 robots and 1 data center. Empty here means no operator has said publicly, not zero adoption in the market.
See also: every chip comparison · AMD Instinct MI250X full page · AMD Instinct MI350 series full page.