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Chip comparison

AMD Instinct MI300X vs AMD Instinct MI350 series

Side-by-side specs

Straight from each vendor's datasheet. Winner in bold: higher throughput, memory, or transistor count; lower power draw or price. Sparse (2:4) throughput roughly doubles the FP8/INT8 numbers shown.

FieldAMD Instinct MI300XAMD Instinct MI350 series
Process nodeTSMC N5 + N6 (chiplet)TSMC N3 (chiplet)
Transistors (B)153
TDP750 W1000 W
Memory192 GB HBM3288 GB HBM3e
Memory bandwidth5,300 GB/s8,000 GB/s
FP16 (dense)1,307 TFLOPS2,300 TFLOPS
BF16 (dense)1,307 TFLOPS2,300 TFLOPS
FP8 (dense)2,614 TFLOPS4,600 TFLOPS
INT8 (dense)2,614 TOPS4,600 TOPS
Launch price (list)$15,000
Form factorOAMOAM
Announced2023-12-062025-06-12
Released2024-01-012025-10-01

Robots running AMD Instinct MI300X

No robots publicly running it yet.

Robots running AMD Instinct MI350 series

No robots publicly running it yet.

Data centers with AMD Instinct MI300X

No data centers publicly running it yet.

Data centers with AMD Instinct MI350 series

Common questions

AMD Instinct MI300X vs AMD Instinct MI350 series: which is faster for training?

AMD Instinct MI350 series has 1.76x the dense FP8 throughput of the other (AMD Instinct MI300X: 2,614 TFLOPS; AMD Instinct MI350 series: 4,600 TFLOPS). Real-world training speed also depends on memory bandwidth, interconnect, and software stack: see the spec diff for those inputs.

AMD Instinct MI300X vs AMD Instinct MI350 series: which has more memory?

AMD Instinct MI350 series carries more HBM (AMD Instinct MI300X: 192 GB HBM3; AMD Instinct MI350 series: 288 GB HBM3e). Memory capacity sets the largest model that fits on one chip without partitioning; memory bandwidth sets inference throughput.

AMD Instinct MI300X vs AMD Instinct MI350 series: which is more power-efficient?

Dense FP8 TFLOPS per watt: AMD Instinct MI300X 3.49 (2,614 ÷ 750 W); AMD Instinct MI350 series 4.60 (4,600 ÷ 1000 W). AMD Instinct MI350 series wins at the die level; system-level efficiency also depends on cooling and interconnect.

AMD Instinct MI300X vs AMD Instinct MI350 series: which is more widely used?

AMD Instinct MI300X: 0 robots and 0 data centers publicly running it. AMD Instinct MI350 series: 0 robots and 1 data center. Empty here means no operator has said publicly, not zero adoption in the market.

See also: every chip comparison · AMD Instinct MI300X full page · AMD Instinct MI350 series full page.