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Chip comparison

AMD Instinct MI350 series vs NVIDIA L40S

Side-by-side specs

Straight from each vendor's datasheet. Winner in bold: higher throughput, memory, or transistor count; lower power draw or price. Sparse (2:4) throughput roughly doubles the FP8/INT8 numbers shown.

FieldAMD Instinct MI350 seriesNVIDIA L40S
Process nodeTSMC N3 (chiplet)TSMC 4N
Transistors (B)76.3
TDP1000 W350 W
Memory288 GB HBM3e48 GB GDDR6
Memory bandwidth8,000 GB/s864 GB/s
FP16 (dense)2,300 TFLOPS362 TFLOPS
BF16 (dense)2,300 TFLOPS362 TFLOPS
FP8 (dense)4,600 TFLOPS733 TFLOPS
INT8 (dense)4,600 TOPS733 TOPS
Form factorOAMPCIe
Announced2025-06-122023-08-08
Released2025-10-01

Robots running AMD Instinct MI350 series

No robots publicly running it yet.

Robots running NVIDIA L40S

No robots publicly running it yet.

Data centers with AMD Instinct MI350 series

Data centers with NVIDIA L40S

No data centers publicly running it yet.

Common questions

AMD Instinct MI350 series vs NVIDIA L40S: which is faster for training?

AMD Instinct MI350 series has 6.28x the dense FP8 throughput of the other (AMD Instinct MI350 series: 4,600 TFLOPS; NVIDIA L40S: 733 TFLOPS). Real-world training speed also depends on memory bandwidth, interconnect, and software stack: see the spec diff for those inputs.

AMD Instinct MI350 series vs NVIDIA L40S: which has more memory?

AMD Instinct MI350 series carries more HBM (AMD Instinct MI350 series: 288 GB HBM3e; NVIDIA L40S: 48 GB GDDR6). Memory capacity sets the largest model that fits on one chip without partitioning; memory bandwidth sets inference throughput.

AMD Instinct MI350 series vs NVIDIA L40S: which is more power-efficient?

Dense FP8 TFLOPS per watt: AMD Instinct MI350 series 4.60 (4,600 ÷ 1000 W); NVIDIA L40S 2.09 (733 ÷ 350 W). AMD Instinct MI350 series wins at the die level; system-level efficiency also depends on cooling and interconnect.

AMD Instinct MI350 series vs NVIDIA L40S: which is more widely used?

AMD Instinct MI350 series: 0 robots and 1 data center publicly running it. NVIDIA L40S: 0 robots and 0 data centers. Empty here means no operator has said publicly, not zero adoption in the market.

See also: every chip comparison · AMD Instinct MI350 series full page · NVIDIA L40S full page.