| Netrality 1102 Grand (Kansas City) | Netrality Data Centers | Kansas City | operating | - |
| Meta Kansas City Data Center | Meta | Kansas City | operating | - |
| LightEdge Kansas City Data Center | LightEdge Solutions | Kansas City | operating | - |
| Kansas City | Iron Mountain Data Centers | Kansas City | operating | - |
| Iron Mountain Kansas Underground | Iron Mountain | Kansas City | operating | - |
| 1102 Grand | Netrality Data Centers | Kansas City | operating | - |
| St. Louis - Millpark Data Center | TierPoint | Maryland Heights | operating | - |
| AWS New Florence Campus (Project Green) | Amazon Web Services | New Florence | planned | - |
| ARY Investments Marshfield Data Center (Rifle Range Road) | ARY Investments | Marshfield | announced | - |
| Cerner Lee's Summit Data Center | Oracle Health (Cerner) | Lee's Summit | operating | - |
| Mastercard Global Technology Campus Data Center | Mastercard | O'Fallon | operating | - |
| Research Computing Support Services Data Center (Hellbender) | University of Missouri | Columbia | operating | - |
| Edward Jones Data Center | Edward Jones | Maryland Heights | operating | - |
| IT Renaissance Data Center | Centene Corporation | O'Fallon | operating | - |
| USDA Enterprise Data Center Kansas City | U.S. Department of Agriculture | Kansas City | operating | - |
| Walmart Jane Data Center | Walmart | Jane | operating | - |
| TierPoint Kansas City | TierPoint | Kansas City | operating | - |
| Nebius Independence Campus | Nebius | Independence | under construction | - |
| Nebius Kansas City Deployment | Nebius | Kansas City | operating | - |
| Kansas City Data Center | Google | Kansas City | under construction | - |
| New Florence Data Center | Google | New Florence | announced | - |
| Lincoln Rackhouse Kansas City (Airworld) | Lincoln Property Company (Lincoln Rackhouse) | Kansas City | operating | - |
| Montgomery County Data Center | Google | Montgomery | planned | - |
| Google New Florence Data Center Campus | Google | New Florence | announced | - |
| AWS Montgomery County Campus (Project Green) | Amazon Web Services | New Florence | planned | - |
| Metrobloks Liberty Campus | Metrobloks | Liberty | planned | - |
| CRG Festus Data Center | CRG | Festus | planned | - |
| Project Mica (Google Kansas City Campus #2) | Google | Kansas City | under construction | - |
| The Mountain Complex (Jack Henry backup data center) | Jack Henry & Associates | Branson | operating | - |
| Jasper County Powered Data Park | Geronimo Power | Joplin | planned | - |
| Rocky Branch Creek Technology Park | Diode Ventures | Kansas City | under construction | - |
| Festus Data Center Campus | CRG (Clayco) | Festus | planned | - |
| Crusoe Warrenton Campus | Crusoe | Warrenton | under construction | - |
| Crusoe Callaway County Campus (Kingdom City) | Crusoe | Kingdom City | planned | - |
| Gateway Digital Campus | Provident Data Centers | Villa Ridge | planned | - |
| Hostirian Data Center (11756 Borman Dr) | Hostirian | Maryland Heights | operating | - |
| Project Mica | Google | Kansas City | under construction | 700 MW |
| White Cloud Acres Data Center | ReLoad (Scale Microgrids) | Maryville | planned | 600 MW |
| Cielo Kansas City Data Center | Cielo Digital Infrastructure | Kansas City | planned | 500 MW |
| Cloverleaf Troy Data Center Campus | Cloverleaf Infrastructure | Troy | planned | 500 MW |
| Metrobloks Liberty Data Center Campus | Metrobloks | Liberty | announced | 150 MW |
| Edged Kansas City | Edged Energy | Kansas City | under construction | 24 MW |
| Lambda Kansas City | Lambda | Kansas City | under construction | 24 MW |
| Bluebird Underground | Bluebird Network | Springfield | operating | 6 MW |
| Nebius Kansas City (Patmos) | Nebius | Kansas City | operating | 5 MW |