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Chip comparison

AMD Instinct MI350 series vs NVIDIA GB300 (Blackwell Ultra)

Side-by-side specs

Straight from each vendor's datasheet. Winner in bold: higher throughput, memory, or transistor count; lower power draw or price. Sparse (2:4) throughput roughly doubles the FP8/INT8 numbers shown.

FieldAMD Instinct MI350 seriesNVIDIA GB300 (Blackwell Ultra)
Process nodeTSMC N3 (chiplet)TSMC 4NP
TDP1000 W1400 W
Memory288 GB HBM3e288 GB HBM3e
Memory bandwidth8,000 GB/s8,000 GB/s
FP16 (dense)2,300 TFLOPS
BF16 (dense)2,300 TFLOPS
FP8 (dense)4,600 TFLOPS5,000 TFLOPS
INT8 (dense)4,600 TOPS
Form factorOAMSuperchip (Blackwell Ultra + Grace)
Announced2025-06-122025-03-18
Released2025-10-012025-11-01

Robots running AMD Instinct MI350 series

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Robots running NVIDIA GB300 (Blackwell Ultra)

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Data centers with AMD Instinct MI350 series

Data centers with NVIDIA GB300 (Blackwell Ultra)

Common questions

AMD Instinct MI350 series vs NVIDIA GB300 (Blackwell Ultra): which is faster for training?

NVIDIA GB300 (Blackwell Ultra) has 1.09x the dense FP8 throughput of the other (AMD Instinct MI350 series: 4,600 TFLOPS; NVIDIA GB300 (Blackwell Ultra): 5,000 TFLOPS). Real-world training speed also depends on memory bandwidth, interconnect, and software stack: see the spec diff for those inputs.

AMD Instinct MI350 series vs NVIDIA GB300 (Blackwell Ultra): which has more memory?

NVIDIA GB300 (Blackwell Ultra) carries more HBM (AMD Instinct MI350 series: 288 GB HBM3e; NVIDIA GB300 (Blackwell Ultra): 288 GB HBM3e). Memory capacity sets the largest model that fits on one chip without partitioning; memory bandwidth sets inference throughput.

AMD Instinct MI350 series vs NVIDIA GB300 (Blackwell Ultra): which is more power-efficient?

Dense FP8 TFLOPS per watt: AMD Instinct MI350 series 4.60 (4,600 ÷ 1000 W); NVIDIA GB300 (Blackwell Ultra) 3.57 (5,000 ÷ 1400 W). AMD Instinct MI350 series wins at the die level; system-level efficiency also depends on cooling and interconnect.

See also: every chip comparison · AMD Instinct MI350 series full page · NVIDIA GB300 (Blackwell Ultra) full page.