| SSA National Computer Center (former) | Social Security Administration | Woodlawn | decommissioned | - |
| Lincoln Rackhouse Silver Spring | Lincoln Property Company (Lincoln Rackhouse) | Silver Spring | operating | - |
| AWS Calvert County Campus (Prince Frederick) | Amazon Web Services | Prince Frederick | planned | - |
| NASA Center for Climate Simulation | NASA Goddard Space Flight Center | Greenbelt | operating | - |
| NIH Biowulf High Performance Computing Center | National Institutes of Health | Bethesda | operating | - |
| Quantum Frederick | Quantum Loophole | Adamstown | under construction | - |
| TierPoint Baltimore (BAL) | TierPoint | Baltimore | operating | - |
| AWS BWI | Amazon Web Services | Owings Mills | operating | - |
| Annapolis Data Center | Maryland Department of General Services | Annapolis | operating | - |
| Census Bureau Bowie Computer Center | U.S. Census Bureau | Bowie | operating | - |
| CyberNAP | AiNET | Glen Burnie | operating | - |
| NASA Center for Climate Simulation (NCCS) | National Aeronautics and Space Administration | Greenbelt | operating | - |
| Advanced Research Computing at Hopkins (Rockfish) | Johns Hopkins University | Baltimore | operating | - |
| ByteGrid MDC-1 (Silver Spring) | ByteGrid | Silver Spring | operating | - |
| ByteGrid MDC-2 (Silver Spring) | ByteGrid | Silver Spring | operating | - |
| ByteGrid Annapolis | ByteGrid | Annapolis | operating | - |
| Comcast Nottingham Data Center | Comcast | Baltimore | operating | - |
| TierPoint Baltimore Data Center | TierPoint | Baltimore | operating | - |
| Aligned IAD-04 | Aligned Data Centers | Frederick | operating | - |
| Baltimore - BWI Data Center | TierPoint | Linthicum Heights | operating | - |
| Rowan Bauxite II (Quantum Frederick Campus) | Rowan Digital Infrastructure | Adamstown | planned | - |
| Rowan Bauxite III (Quantum Frederick Campus) | Rowan Digital Infrastructure | Adamstown | planned | - |
| Morgantown Data Center (Morgantown Generation Station) | TeraWulf | Newburg | planned | - |
| TeraWulf Morgantown Data Center Campus | TeraWulf Inc. | Newburg | announced | 1000 MW |
| Brightseat Tech Park (Landover Mall Data Center) | Lerner Enterprises / Brightseat Associates LLC | Landover | planned | 820 MW |
| Brightseat Tech Park (former Landover Mall site) | Lerner Enterprises | Landover | planned | 820 MW |
| TeraWulf Chesapeake Data and Energy | TeraWulf | Charles County | planned | 800 MW |
| Chesapeake Data & Energy Campus | TeraWulf | Charles County | planned | 800 MW |
| Bauxite (Quantum Frederick Campus) | Rowan Digital Infrastructure | Adamstown | under construction | 630 MW |
| Appeal Digital Park | Natelli Holdings | Lusby | planned | 300 MW |
| Rowan Bauxite I / AWS BWI (Quantum Frederick Campus) | Rowan Digital Infrastructure | Adamstown | under construction | 300 MW |
| Atmosphere Dickerson Data Center Campus | Atmosphere Data Centers | Dickerson | planned | 300 MW |
| AWS Quantum Frederick / Rowan Campus | Amazon Web Services | Frederick | under construction | 258 MW |
| Woodlawn Data Center (1500 Woodlawn Drive) | Security Land and Development | Woodlawn | planned | 150 MW |
| One Market Center | AiNET | Baltimore | operating | 80 MW |
| Aligned IAD-04 (Quantum Frederick Campus) | Aligned Data Centers | Adamstown | under construction | 72 MW |
| Aligned IAD-06 (Quantum Frederick Campus) | Aligned Data Centers | Adamstown | under construction | 72 MW |
| TPC Konterra 1 Data Center | TPC Data Centers (Twin Palms Capital) | Laurel | planned | 20 MW |
| Social Security Administration National Support Center | Social Security Administration | Urbana | operating | 10 MW |
| Expedient Baltimore Data Center | Expedient | Baltimore | operating | 2.3 MW |